inhibitory effects of six allium species on ?-amylase enzyme activity

نویسندگان

n yousefian

چکیده

diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia. the management of the blood glucose level is a critical strategy in the control of diabetes complications. inhibitors of carbohydrate hydrolyzing enzymes have been useful as oral hypoglycemic drugs for the control of hyperglycemia especially in patients with type ii disables mellitus. the goal of the present study was to investigate the inhibitory effects of six selected allium species (a. akaka, a. ampeloprasum subsp. iranicum, a. cepa, a. hirtifolium, a. porrum and a. sativum) on ?-amylase enzyme using an in vitro model. according to the results, ethanol extracts of a. akaka, a. sativum, a. porrum and a. cepa were found to have a favorable ?-amylase inhibitory activity with ic50 values of 16.74, 17.95, 15.73 and 16.36 mg/ml, respectively and they did not reveal any significant differences in their ic50 values (p>0.05). however, the two other allium species tested (a. ampeloprasum subsp. iranicum and a. hirtifolium) did not show valuable inhibitory activity.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Inhibitory Effects of Six Allium Species on ?-Amylase Enzyme Activity

Diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia. The management of the blood glucose level is a critical strategy in the control of diabetes complications. Inhibitors of carbohydrate hydrolyzing enzymes have been useful as oral hypoglycemic drugs for the control of hyperglycemia especially in patients with type II disables mellitus. The goal of the present study...

متن کامل

Inhibitory Effects of Six Allium Species on ?-Amylase Enzyme Activity

Diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia. The management of the blood glucose level is a critical strategy in the control of diabetes complications. Inhibitors of carbohydrate hydrolyzing enzymes have been useful as oral hypoglycemic drugs for the control of hyperglycemia especially in patients with type II disables mellitus. The goal of the present study...

متن کامل

?-Amylase Inhibitory Activities of Six Salvia Species

?-Amylase inhibitory activities of ethanol extracts from six selected Iranian Salvia species (S. hydrangea DC., S. hypoleuca Benth., S. officinalis L., S. reuterana Boiss., S. verticillata L. and S. virgata Jacq.) were examined, using in vitro model. In addition, antioxidant capacities (DPPH• radical scavenging) and total flavonoid cotents of the extracts were also determined. The results showe...

متن کامل

?-Amylase Inhibitory Activities of Six Salvia Species

?-Amylase inhibitory activities of ethanol extracts from six selected Iranian Salvia species (S. hydrangea DC., S. hypoleuca Benth., S. officinalis L., S. reuterana Boiss., S. verticillata L. and S. virgata Jacq.) were examined, using in vitro model. In addition, antioxidant capacities (DPPH• radical scavenging) and total flavonoid cotents of the extracts were also determined. The results showe...

متن کامل

?-amylase inhibitory activities of six salvia species

?-amylase inhibitory activities of ethanol extracts from six selected iranian salvia species (s. hydrangea dc., s. hypoleuca benth., s. officinalis l., s. reuterana boiss., s. verticillata l. and s. virgata jacq.) were examined, using in vitro model. in addition, antioxidant capacities (dpph• radical scavenging) and total flavonoid cotents of the extracts were also determined. the results showe...

متن کامل

Influence of Three Morus Species Extracts on ?-Amylase Activity

Diabetes mellitus is one of the most common endocrine diseases and its type II is the major form of diabetes, accounting for 90% of cases worldwide. The inhibition of carbohydrate hydrolyzing enzymes such as ?-amylase can be an important strategy in the control of blood glucose levels in patients with type II diabetes. In this investigation, three Morus species, M. alba, M. alba var. nigra and ...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of pharmaceutical research

جلد ۲۰۰۹، شماره ۱، صفحات ۵۳-۵۷

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023